Cediranib for Metastatic Alveolar Soft Part Sarcoma
نویسندگان
چکیده
منابع مشابه
Cediranib for metastatic alveolar soft part sarcoma.
PURPOSE Alveolar soft part sarcoma (ASPS) is a rare, highly vascular tumor, for which no effective standard systemic treatment exists for patients with unresectable disease. Cediranib is a potent, oral small-molecule inhibitor of all three vascular endothelial growth factor receptors (VEGFRs). PATIENTS AND METHODS We conducted a phase II trial of once-daily cediranib (30 mg) given in 28-day c...
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The aim of the present study was to identify the target genes of cediranib and the associated signaling pathways in alveolar soft part sarcoma (ASPS). A microarray dataset (GSE32569) was obtained from the Gene Expression Omnibus database. The R software package was used for data normalization and screening of differentially expressed genes (DEGs). The Database for Annotation, Visualization and ...
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pherson in 1952 3). Its histogenesis is still uncertain, and there are few cytological articles about this tumor15). We tried cytological analysis of touch preparation of a case of alveolar soft part sarcoma and report on its cytological features. On the other hand, metastatic renal adenocarcinoma is necessary to be differentiated from alveolar soft part sarcoma, so we also performed imprint pr...
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A 33-year-old woman was referred to Iida Municipal Hospital because of left back pain. Computed tomography showed a tumor (17 x 11 x 10 cm) in the left retroperitoneal space. T1- and T2-weighted magnetic resonance imaging showed an inhomogeneous mass with marginal blood vessels. The tumor was resected via lumbar oblique incision with the thoraco-abdominal approach. The tumor weighed 1800 g and ...
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Alveolar soft part sarcoma (ASPS) is a very rare sarcoma, report <1% of all soft tissue tumor. Majority of cases were young adult and tumor occurred in lower extremities and trunk. Here, we present a case of 53-year-old Thai female with rapidly glowing mass over her right forearm. The magnetic resonance imaging scan demonstrated a hypervascular mass with multiple feeding vessels located in flex...
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ژورنال
عنوان ژورنال: Journal of Clinical Oncology
سال: 2013
ISSN: 0732-183X,1527-7755
DOI: 10.1200/jco.2012.47.4288